2022 10-18 CC PACKET - Laserfiche WebLink

Home

The U.S. Food and Drug Administration has approved one drug using CBD — Epidiolex —which.treats seizures related to several diseases: No other CBD products are allowed to make health claims. THC —Delta-9 tetrahydrocannabinol (THC) is the most potent -and well-known cannabinoid naturally occurring in high concentrations in cannabis plants, namely the flower buds. THC causes.a high by bonding with and overwhelming the body's endocannabinoid receptors. Humans have been; getting high on and medicating with THC for at least 2,500.years; .gSc9Ld1Ilgl.�apublished W the js21;maJ,Sdgnce Advances fh_ttps:([_, _._ssaence org/doi110.1126/sciadv.aawl391? _ga=2.59273070.2100662538.1663178096-80962128.166 09f) . It is used at least occasionally by 16% of American adults, according -to a Gallup pollreleased in July. Th. compare, about 60% ofAmerican adults drink alcohol pa�slop. 8tudiesiia3Nconcluded bJ=://wwrv.ncbi.nlm.nih.gQy[pmQ ar cles/PMC59680201#_CRl)_THC is effective for pain relief and boosting_appetite[htto�[[pubmed.ncbi.nlm.nih.gov/19367510/l , and 37 states have adopted medical marijuana programs. While nearly impossible to ingest a fatal dose of THC, long-term and high -dose usage of the drug can cause negative pvsical and mental health outcomes Shuns:/Ayww.ncbi.nim.nihgQy[pmc/articles/IMC64167_43Z), though more research is needed to determine causation vs. correlation. DeIta-8 THC -- Despite a slew of states legalizing it federal law still bans the sale and possession of delta-9. THC. But there are related chemicals that have a similar chemical structure and effect that are federally legaL.Since the 2018 Farm Bill legally separated hemp and its extracts: from marijuana, high -inducing delta-8 THC has been converted from .hemp-de#ved..CBD and sold. in it legal. gray area. It produces'a sin-iiiar btu milder high compared to delta-9 THC. An important note.for Minnesota: The state% THC edible law appliesto all forms. of THC. This means vapes:and cannabis buds with more than 03% of any THGare illegal, as are edibles and drinks with more than 5 mg of any THa CBD-onlyvapes and buds can be legally sold in Minnesota. Extraction. —Turning CBD-rich hemp flower into an increasingly concentrated extract, distillate or isolate requires a ttip to the chemi9rylg& fhtfos //www ncbi.nlm.nih.S41pmr/articles/PMC8292SM Usually the >in. step involves heating plant ntaterialto activate cannabinoids, a process known as :decarboxylation — though this can follow the extraction process. At commercial operations, extraction happens vA= hemp buds are packed into canisters with carbon dioxide or ethanol: This catiees CBD, fats,.terpenes and some other organic material to separate from the plant•and provides a crude .CBD oiL The crude oil is then filtered and distilled —and often "Winterized"with ethanol or another solvent —to reach a nearly pure CBD end product. The product must be tested to ensure it is free of residual solvents or byproducts. CBD is then added to coconut oil or another "ca mer" oil in various doses to be used in a range of products. Conversion — Once CBD is extracted and purified to an acceptable level, jS fig: chemi�ljy cortyed to other cannabinoids (httvs://cen.acs.orglbiolceical- Ch rg gy/naturaf pxoducts/Aelta- :=:Mge-concerns./99/i31J—including:delta-9 THC. This conversion is the source of most hemp -derived THC on the market, since hemp plants. by def ri tion have very little naturally occurring THC. The coriversion•procew inVdlves.combining pure CBD with a solvent, such as toluene or heptane,.and•a.sf ongackL The -resulting THC is then purified and cleansed ofsolvents, ac#ds and byproduco and mupt be'testmilto prove no unwanted mateiials are*th4-